Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

mRTVP-1, a Novel p53 Target Gene with Proapoptotic Activities

1 May 2002

Abstract excerpt

We identified a novel mouse gene, mRTVP-1, as a p53 target gene using differential display PCR and extensive promoter analysis. The mRTVP-1 protein has 255 amino acids and differs from the human RTVP-1 (hRTVP-1) protein by two short in-frame deletions of two and nine amino acids. RTVP-1 mRNA was induced in multiple cancer cell lines by adenovirus-mediated delivery of p53 and by gamma irradiation or doxorubicin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Molecular Biology Techniques and Applications
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11971968
DOI: 10.1128/mcb.22.10.3345-3357.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

mRTVP-1, a Novel p53 Target Gene with Proapoptotic ActivitiesPMID 11971968Read ↗

Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene clusterSemantic proximity Read ↗

Identification of the <i>Osteopontin</i> gene as a direct target of TP53Semantic proximity Read ↗

Identification and characterization of genes whose expressions are altered in rat 6 fibroblasts transformed by mutant p53(val135).Semantic proximity Read ↗

p53 is required for radiation-induced apoptosis in mouse thymocytes.Semantic proximity Read ↗

Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigenSemantic proximity Read ↗

p53 Stabilization and Accumulation Induced by Human Vaccinia-Related Kinase 1Semantic proximity Read ↗

The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.Semantic proximity Read ↗

VPS35/Retromer-dependent MT1-MMP regulation confers melanoma metastasisSemantic proximity Read ↗

Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumorsSemantic proximity Read ↗

Moloney murine leukemia virus-induced lymphomas in p53-deficient mice: overlapping pathways in tumor development?Semantic proximity Read ↗

Tumor prone phenotype of mice deficient in a novel apoptosis-inducing gene, drs.Semantic proximity Read ↗

Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.