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Article

cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos.

Proceedings of the National Academy of Sciences of the United States of America - 16 Apr 2002

Wallenfang Matthew R, Seydoux Geraldine

Abstract excerpt

CDK7 is a cyclin-dependent kinase proposed to function in two essential cellular processes: transcription and cell cycle regulation. CDK7 is the kinase subunit of the general transcription factor TFIIH that phosphorylates the C-terminal domain (CTD) of RNA polymerase II, and has been shown to be broadly required for transcription in Saccharomyces cerevisiae. CDK7 can also phosphorylate CDKs that promote cell...

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Identifiers

PMID: 11960010
DOI: 10.1073/pnas.082618399
PMCID: PMC122803

Genes

CDK7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos.PMID 11960010Read ↗

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