Article
Delineation of commonly deleted chromosomal regions in meningiomas by high-density single nucleotide polymorphism genotyping arrays.
Genes, chromosomes & cancer - 1 Jun 2012
Tabernero Maria Dolores, Maíllo Angel, Nieto Ana Belen, Diez-Tascón Cristina, Lara Mónica, Sousa Pablo, Otero Alvaro, Castrillo Abel, Patino-Alonso Maria del Carmen, Espinosa Ana, Mackintosh Carlos, de Alava Enrique, Orfao Alberto
Abstract excerpt
Despite recent advances in the identification of the cytogenetic profiles of meningiomas, a significant group of tumors still show normal karyotypes or few chromosomal changes. The authors analyzed the cytogenetic profile of 50 meningiomas using fluorescence in situ hybridization and high-density (500 K) single nucleotide polymorphism (SNP) arrays. Our results confirm that del(22q) (52%) and del(1p) (16%) (common...
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