Article
Ceramic and PMMA particles differentially affect osteoblast phenotype.
Biomaterials - 1 Apr 2002
Lohmann Christoph H, Dean David D, Köster Georg, Casasola David, Buchhorn Gottfried H, Fink Ulrich, Schwartz Zvi, Boyan Barbara D
Abstract excerpt
There is increasing evidence that wear debris particles present in periprosthetic tissues have direct effects on osteoblasts. The nature of the cell response varies with the chemistry of the particle and the number of particles. Most studies have used Ti, Ti-6Al-4V, and ultrahigh molecular weight polyethylene (UHMWPE) particles since these materials are most frequently used in implants and as a result, these...
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