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Article

Pretreatment of bone with osteoclasts affects phenotypic expression of osteoblast-like cells.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jul 2003

Boyan B D, Schwartz Z, Lohmann C H, Sylvia V L, Cochran D L, Dean D D, Puzas J E

Abstract excerpt

Implant surface morphology regulates osteoblast phenotypic expression. Osteoblast sensitivity to non-biologic surfaces suggests that native bone surface features may also affect osteoblast response. To test this, MG63 osteoblast-like cells were grown for 7 days on bovine cortical bone wafers pretreated with rat bone marrow osteoclasts for 0, 10 or 20 days. Response to osteoclast-treated surfaces was compared to...

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PMID: 12798063
DOI: 10.1016/S0736-0266(02)00261-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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