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Article

Molecular Regulation of Na+‐K+‐2C1‐ Cotransporter (NKCC1) and Epithelial Chloride Secretion

1 Jul 2002

Abstract excerpt

Defective regulation of epithelial secretion underlies the clinical manifestations of a number of important human diseases ranging from cystic fibrosis to secretory diarrhea. Although much attention has focused on the role of apical membrane chloride (Cl-) channels in this process, emerging evidence highlights the importance of a basolateral Na+-K+-2Cl- cotransporter (NKCC1) as an independent regulatory site that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11948363
DOI: 10.1007/s00268-002-4059-z

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