Article
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.
Physiological reviews - 1 Apr 2005
Gamba Gerardo
Abstract excerpt
Electroneutral cation-Cl(-) cotransporters compose a family of solute carriers in which cation (Na(+) or K(+)) movement through the plasma membrane is always accompanied by Cl(-) in a 1:1 stoichiometry. Seven well-characterized members include one gene encoding the thiazide-sensitive Na(+)-Cl(-) cotransporter, two genes encoding loop diuretic-sensitive Na(+)-K(+)-2Cl(-) cotransporters, and four genes encoding...
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