Article
WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jan 2003
Choate Keith A, Kahle Kristopher T, Wilson Frederick H, Nelson-Williams Carol, Lifton Richard P
Abstract excerpt
Mutations in WNK1 and WNK4, genes encoding members of a novel family of serine-threonine kinases, have recently been shown to cause pseudohypoaldosteronism type II (PHAII), an autosomal dominant disorder featuring hypertension, hyperkalemia, and renal tubular acidosis. The localization of these k...
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