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Article

Role of Cbl in shear-activation of PI 3-kinase and JNK in endothelial cells.

Biochemical and biophysical research communications - 12 Apr 2002

Miao Hui, Yuan Suli, Wang Yingxiao, Tsygankov Alexander, Chien Shu

Abstract excerpt

Fluid shear stress can activate PI-3 kinase and JNK in vascular endothelial cells. This study was designed to establish the role of Cbl as an upstream molecule in the shear stress activation of PI-3 kinase and JNK. Confluent monolayers of bovine aortic endothelial cells (BAECs) were subjected to a shear stress of 12 dyn/cm(2) over intervals ranging from 0.5 to 30 min. Shear stress increased Cbl phosphorylation to...

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Source

Identifiers

PMID: 11944898
DOI: 10.1006/bbrc.2002.6750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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