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Article

Biomechanical regulation of matrix metalloproteinase-9 in cultured chondrocytes.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Nov 2000

Jin G, Sah R L, Li Y S, Lotz M, Shyy J Y, Chien S

Abstract excerpt

Abnormal mechanical loading of joints may induce degeneration of articular cartilage. Shear stress is one mode of mechanical loading that may regulate chondrocyte metabolism. We investigated the mechanism by which shear stress induces the gene encoding matrix metalloproteinase-9, a mediator of th...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11192249
DOI: 10.1002/jor.1100180608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11192249-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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