Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of mitochondrial and plastid activity of Plasmodium falciparum by minocycline

4 Mar 2002

Abstract excerpt

We previously reported the superior effect of minocycline against drug-resistant Plasmodium falciparum in vitro. Here, we report that RT-PCR for falciparum parasites treated with minocycline revealed reduced levels of RNA transcripts of the mitochondrion-encoded genes such as the COI and Cyb genes, as well as the plastid-encoded RNA polymerase subunit (rpoB/C) gene. However, we detected no apparent effects of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aquaculture disease management and microbiota
Share to Invertebrate Immune Response Mechanisms
Share to Malaria Research and Control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11943197
DOI: 10.1016/s0014-5793(02)02437-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Inhibition of mitochondrial and plastid activity of Plasmodium falciparum by minocyclinePMID 11943197Read ↗

Telithromycin and Quinupristin-Dalfopristin Induce Delayed Death in Plasmodium falciparumSemantic proximity Read ↗

Inhibition of RNA Polymerase by Rifampicin and Rifamycin-Like MoleculesSemantic proximity Read ↗

Tetracyclines Specifically Target the Apicoplast of the Malaria Parasite <i>Plasmodium falciparum</i>Semantic proximity Read ↗

Activity of and development of resistance to corallopyronin A, an inhibitor of RNA polymerase.Semantic proximity Read ↗

Suppression by RNA Polymerase I Inhibitors Varies Greatly Between Distinct RNA Polymerase I Transcribed Genes in Malaria ParasitesSemantic proximity Read ↗

Genetic ablation of the mitochondrial ribosome in <i>Plasmodium falciparum</i> sensitizes the human malaria parasite to antimalarial drugs targeting mitochondrial functionsSemantic proximity Read ↗

Genetic ablation of the mitoribosome in the malaria parasite Plasmodium falciparum sensitizes it to antimalarials that target mitochondrial functionsSemantic proximity Read ↗

PCR correction strategies for malaria drug trials: updates and clarificationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.