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Article

Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18.

Genes & development - 1 Apr 2002

Liu Zhonghao, Xu Jingsong, Colvin Jennifer S, Ornitz David M

Abstract excerpt

Gain of function mutations in fibroblast growth factor (FGF) receptors cause chondrodysplasia and craniosynostosis syndromes. The ligands interacting with FGF receptors (FGFRs) in developing bone have remained elusive, and the mechanisms by which FGF signaling regulates endochondral, periosteal, and intramembranous bone growth are not known. Here we show that Fgf18 is expressed in the perichondrium and that mice...

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Source

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Identifiers

PMID: 11937493
DOI: 10.1101/gad.965602
PMCID: PMC186326

Genes

FGF18
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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