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Article

Fibroblast growth factor receptor signaling crosstalk in skeletogenesis.

Science signaling - 2 Nov 2010

Miraoui Hichem, Marie Pierre J

Abstract excerpt

Fibroblast growth factors (FGFs) play important roles in the control of embryonic and postnatal skeletal development by activating signaling through FGF receptors (FGFRs). Germline gain-of-function mutations in FGFR constitutively activate FGFR signaling, causing chondrocyte and osteoblast dysfunctions that result in skeletal dysplasias. Crosstalk between the FGFR pathway and other signaling cascades controls...

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Source

Identifiers

PMID: 21045207
DOI: 10.1126/scisignal.3146re9

Genes

FGFR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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