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Article

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.

Genes & development - 1 Apr 2002

Ohbayashi Norihiko, Shibayama Masaki, Kurotaki Yoko, Imanishi Mayumi, Fujimori Toshihiko, Itoh Nobuyuki, Takada Shinji

Abstract excerpt

Fibroblast growth factor (FGF) signaling is involved in skeletal development of the vertebrate. Gain-of-function mutations of FGF receptors (FGFR) cause craniosynostosis, premature fusion of the skull, and dwarfism syndromes. Disruption of Fgfr3 results in prolonged growth of long bones and vertebrae. However, the role that FGFs actually play in skeletal development in the embryo remains unclear. Here we show...

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Identifiers

PMID: 11937494
DOI: 10.1101/gad.965702
PMCID: PMC186331

Genes

FGF18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.PMID 11937494Read ↗

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