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Article

FGF and FGFR signaling in chondrodysplasias and craniosynostosis.

Journal of cellular biochemistry - 1 Dec 2005

Marie P J, Coffin J D, Hurley M M

Abstract excerpt

The first experimental mouse model for FGF2 in bone dysplasia was made serendipitously by overexpression of FGF from a constitutive promoter. The results were not widely accepted, rightfully drew skepticism, and were difficult to publish; because of over 2,000 studies published on FGF-2 at the time (1993), only a few reported a role of FGF-2 in bone growth and differentiation. However, mapping of human dwarfisms...

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Source

Identifiers

PMID: 16149058
DOI: 10.1002/jcb.20582

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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