Article
DIVERGE: phylogeny-based analysis for functional-structural divergence of a protein family.
Bioinformatics (Oxford, England) - 1 Mar 2002
Gu Xun, Vander Velden Kent
Abstract excerpt
SUMMARY: DetectIng Variability in Evolutionary Rates among GEnes (DIVERGE) is a software system to study functional divergence of a protein family by detecting site-specific change in evolutionary rate using a multiple alignment of amino acid sequences for a given phylogenetic tree. The program first conducts a statistical test for site-specific rate shifts along the tree, and predicting candidate amino acid...
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