Article
Exploring the relationship between sequence similarity and accurate phylogenetic trees.
Molecular biology and evolution - 1 Nov 2006
Cantarel Brandi L, Morrison Hilary G, Pearson William
Abstract excerpt
We have characterized the relationship between accurate phylogenetic reconstruction and sequence similarity, testing whether high levels of sequence similarity can consistently produce accurate evolutionary trees. We generated protein families with known phylogenies using a modified version of the PAML/EVOLVER program that produces insertions and deletions as well as substitutions. Protein families were evolved...
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