Article
Insertion of bitopic membrane proteins into the inner membrane of mitochondria involves an export step from the matrix.
The Journal of biological chemistry - 14 Jun 2002
Baumann Frank, Neupert Walter, Herrmann Johannes M
Abstract excerpt
The mitochondrial inner membrane contains a large number of polytopic proteins that are derived from prokaryotic ancestors of mitochondria. Little is known about the intramitochondrial sorting of these proteins. We chose two proteins of known topology as examples to study the pathway of insertion into the inner membrane; Mrs2 and Yta10 are bitopic proteins that expose negatively charged loops of different...
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