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Article

The influence on the schizophrenic symptoms by the DRD2Ser/Cys311 and -141C Ins/Del polymorphisms.

Psychiatry and clinical neurosciences - 1 Feb 2002

Himei Akio, Koh Jun, Sakai Jun, Inada Yasushi, Akabame Kazuyo, Yoneda Hiroshi

Abstract excerpt

The hyperactivity of dopaminergic systems is one of the major etiological hypotheses of schizophrenia. The major support for this hypothesis is that effective antipsychotic drugs bind to dopamine receptors and improve acute schizophrenic symptoms. For this reason, we investigated the allelic association between schizophrenia and polymorphisms of the DRD2 genes for the Ser/Cys311 and -141C Ins/Del. The subjects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Dopamine D2

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Source

Identifiers

PMID: 11929577
DOI: 10.1046/j.1440-1819.2002.00935.x

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The influence on the schizophrenic symptoms by the DRD2Ser/Cys311 and -141C Ins/Del polymorphisms.PMID 11929577Read ↗

Association between the DRD2-141C Insertion/Deletion polymorphism and schizophrenia.Semantic proximity Read ↗

Influence of DRD2 polymorphisms on the clinical outcomes of patients with schizophrenia.Semantic proximity Read ↗

Association between a promoter polymorphism in the dopamine D2 receptor gene and schizophrenia.Semantic proximity Read ↗

Association between Ser311Cys polymorphism in the dopamine D2 receptor gene and schizophrenia risk: a meta-analysis in Asian populations.Semantic proximity Read ↗

-141C Ins/Del polymorphism of the dopamine D2 receptor gene is associated with schizophrenia in a Spanish population.Semantic proximity Read ↗

Dopamine D2 receptor gene -141C Insertion/Deletion polymorphism in Turkish schizophrenic patients.Semantic proximity Read ↗

The -141C Ins/Del and Taq1A polymorphism in the dopamine D2 receptor gene may confer susceptibility to schizophrenia in Asian populations.Semantic proximity Read ↗

Functional polymorphism of -141C Ins/Del in the dopamine D2 receptor gene promoter and schizophrenia.Semantic proximity Read ↗

The Cys allele of the DRD2 Ser311Cys polymorphism has a dominant effect on risk for schizophrenia: evidence from fixed- and random-effects meta-analyses.Semantic proximity Read ↗

Dopamine DRD2/Cys311 is not associated with chronic schizophrenia.Semantic proximity Read ↗

Genetic polymorphisms in the dopamine-2 receptor (DRD2), dopamine-3 receptor (DRD3), and dopamine transporter (SLC6A3) genes in schizophrenia: Data from an association study.Semantic proximity Read ↗

A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia.Semantic proximity Read ↗

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