Article
Genetic polymorphisms in the dopamine-2 receptor (DRD2), dopamine-3 receptor (DRD3), and dopamine transporter (SLC6A3) genes in schizophrenia: Data from an association study.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Feb 2010
Sáiz Pilar A, García-Portilla M Paz, Arango Celso, Morales Blanca, Arias Bárbara, Corcoran Paul, Fernández Juan M, Alvarez Victoria, Coto Eliecer, Bascarán María-Teresa, Bousoño Manuel, Fañanas Lourdes, Bobes Julio
Abstract excerpt
OBJECTIVE: To investigate the association between dopaminergic polymorphisms [DRD2 -141C Ins/Del, DRD3 Ser9Gly, and SLC6A3 VNTR] and schizophrenia. METHODS: Two hundred and eighty-eight outpatients with schizophrenia (DSM-IV criteria) [mean age (SD)=36.4 (12.4), 60.1% males] and 421 unrelated healthy controls [mean age (SD)=40.6 (11.3), 51.3% males] from a homogeneous Spanish Caucasian population were genotyped...
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