Article
Association between a promoter polymorphism in the dopamine D2 receptor gene and schizophrenia.
Schizophrenia research - 9 Nov 1999
Jönsson E G, Nöthen M M, Neidt H, Forslund K, Rylander G, Mattila-Evenden M, Asberg M, Propping P, Sedvall G C
Abstract excerpt
Genetic factors and dopamine receptor dysfunction have been implicated in the pathophysiology of schizophrenia. Recently, an association between a putative functional promoter polymorphism (-141C Ins/Del) in the dopamine D2 receptor gene and schizophrenia was reported. We investigated unrelated Swedish schizophrenic patients (n = 129) and control subjects (n = 179) for the same polymorphism. Similarly to a...
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