Article
-141C Ins/Del polymorphism of the dopamine D2 receptor gene is associated with schizophrenia in a Spanish population.
Psychiatric genetics - 1 Jun 2008
Lafuente Amalia, Bernardo Miquel, Mas Sergi, Crescenti Anna, Aparici Monica, Gassó Patricia, Goti Javier, Sanchez Vanessa, Catalan Rosa, Carne Xavier
Abstract excerpt
OBJECTIVE: In this study we examined the relationship between dopamine D2 receptor (DRD2) polymorphisms (TaqIA, TaqIB, -141C Ins/Del) and dopamine D3 receptor (DRD3) Ser9Gly polymorphism and the risk of schizophrenia in a Spanish population. METHODS: Two hundred and forty-three schizophrenia patients and 291 healthy controls from the general population participated in a case-control study. RESULTS: No significant...
Topics
- Age Distribution
- Alleles
- Case-Control Studies
- Cytosine
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Male
- Middle Aged