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Article

c‐Src/Lyn kinases activate <i>Helicobacter pylori</i> CagA through tyrosine phosphorylation of the EPIYA motifs

1 Feb 2002

Abstract excerpt

The human pathogen Helicobacter pylori colonizes the mucous layer of the stomach. During parasitic infection, freely swimming bacteria adhere to the gastric epithelial cells and trigger intracellular signalling pathways. This process requires the translocation of the effector protein CagA into the host cell through a specialized type IV secretion system encoded in the cag pathogenicity island. Following transfer,...

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PMID: 11929545
DOI: 10.1046/j.1365-2958.2002.02781.x

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c‐Src/Lyn kinases activate <i>Helicobacter pylori</i> CagA through tyrosine phosphorylation of the EPIYA motifsPMID 11929545Read ↗

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