Article
Endophilin B is required for the Drosophila oocyte to endocytose yolk downstream of Oskar.
Development (Cambridge, England) - 1 Feb 2014
Tsai Yi-Cheng, Chiang Wei, Liou Willisa, Lee Wei-Hao, Chang Yu-Wei, Wang Pei-Yu, Li Yi-Chen, Tanaka Tsubasa, Nakamura Akira, Pai Li-Mei
Abstract excerpt
The nutritional environment is crucial for Drosophila oogenesis in terms of controlling hormonal conditions that regulate yolk production and the progress of vitellogenesis. Here, we discovered that Drosophila Endophilin B (D-EndoB), a member of the endophilin family, is required for yolk endocytosis as it regulates membrane dynamics in developing egg chambers. Loss of D-EndoB leads to yolk content reduction,...
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