Article
Multiplexed analysis of post-PCR fluorescence-labeled microsatellite alleles and statistical evaluation of their imbalance in brain tumors.
Japanese journal of cancer research : Gann - 1 Mar 2002
Yoshimoto Koji, Iwaki Toru, Inamura Takanori, Fukui Masashi, Tahira Tomoko, Hayashi Kenshi
Abstract excerpt
Detection of the loss of chromosomal regions in cancerous tissues has diagnostic and prognostic relevance, and the development of a reliable and cost-effective technique for this is clinically important. Here we present an efficient technique for quantitative detection of microsatellite alleles, using a post-PCR fluorescence-labeling procedure and multiplexed analysis. We also present a new statistical method for...
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