Article
Mutations of p53, c-kit, K-ras, and beta-catenin gene in non-Hodgkin's lymphoma of adrenal gland.
Japanese journal of cancer research : Gann - 1 Mar 2002
Nakatsuka Shin-ichi, Hongyo Tadashi, Syaifudin Mukh, Nomura Taisei, Shingu Norihisa, Aozasa Katsuyuki
Abstract excerpt
Malignant lymphoma of the adrenal gland is a rare disease, usually with diffuse large cell morphology and B-cell immunophenotype, and often associated with Epstein-Barr virus infection. In this study, mutations of p53, c-kit, K-ras, and beta-catenin gene were analyzed in 17 cases (13 males and four females with ages ranging from 25 to 84 years) of such lymphomas by polymerase chain reaction-single strand...
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