Article
Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Apr 2002
Gu Yanghong, McIlwain Kellie L, Weeber Edwin J, Yamagata Takanori, Xu Bisong, Antalffy Barbara A, Reyes Christine, Yuva-Paylor Lisa, Armstrong Dawna, Zoghbi Huda, Sweatt J David, Paylor Richard, Nelson David L
Abstract excerpt
FRAXE mental retardation results from expansion and methylation of a CCG trinucleotide repeat located in exon 1 of the X-linked FMR2 gene, which results in transcriptional silencing. The product of FMR2 is a member of a family of proteins rich in serine and proline, members of which have been ass...
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