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Article

BMP9 protects septal neurons from axotomy-evoked loss of cholinergic phenotype.

PloS one - 1 Jan 2011

Lopez-Coviella Ignacio, Mellott Tiffany J, Schnitzler Aletta C, Blusztajn Jan K

Abstract excerpt

BACKGROUND: Cholinergic projection from the septum to the hippocampus is crucial for normal cognitive function and degeneration of cells and nerve fibers within the septohippocampal pathway contributes to the pathophysiology of Alzheimer's disease. Bone morphogenetic protein (BMP) 9 is a cholinergic differentiating factor during development both in vivo and in vitro. METHODOLOGY/PRINCIPAL FINDINGS: To determine...

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Source

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Identifiers

PMID: 21695154
DOI: 10.1371/journal.pone.0021166
PMCID: PMC3113905

Genes

NGF
CHAT
FGF2
NGFR
NTRK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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