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Article

Investigation of linkage and association/linkage disequilibrium of HLA A-, DQA1-, DQB1-, and DRB1-alleles in 69 sib-pair- and 89 trio-families with schizophrenia.

American journal of medical genetics - 8 Apr 2002

Schwab Sibylle G, Hallmayer Joachim, Freimann Julia, Lerer Bernard, Albus Margot, Borrmann-Hassenbach Margitta, Segman Ronnen H, Trixler Matyas, Rietschel Marcella, Maier Wolfgang, Wildenauer Dieter B

Abstract excerpt

The hypothesis that HLA antigens confer susceptibility to schizophrenic disorders has been tested by studying linkage and association in a family sample with 69 sib-pair families. Suggestive evidence for linkage was obtained by nonparametric multipoint LOD score analysis with a maximum around DQB CAR (P = 0.0004), a microsatellite marker that is in linkage disequilibrium with the HLA antigen DQB1. Spurious...

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PMID: 11920855
DOI: 10.1002/ajmg.10307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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