Article
A transmission/disequilibrium study of the DRB1*04 gene locus on chromosome 6p21.3 with schizophrenia.
Schizophrenia research - 27 Jul 1998
Wright P, Dawson E, Donaldson P T, Underhill J A, Sham P C, Zhao J, Gill M, Nanko S, Owen M J, McGuffin P, Murray R M
Abstract excerpt
Patients with schizophrenia rarely develop rheumatoid arthritis, an autoimmune disease that exhibits genetic association with the HLA DRB1*04 gene. We previously investigated the hypothesis that schizophrenia is negatively associated with DRB1*04, and found that only half the expected number of s...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 6
- Genotype
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Linkage Disequilibrium
- Pedigree
- Polymerase Chain Reaction
- Schizophrenia