Article
Search for schizophrenia susceptibility variants at the HLA-DRB1 locus among a British population.
Immunogenetics - 1 Jan 2013
Halley Lorna, Doherty Mary K, Megson Ian L, McNamara Neil, Gadja Andy, Wei Jun
Abstract excerpt
Schizophrenia is a complex mental disorder with unknown aetiology. Both candidate gene and genome-wide association (GWA) studies suggest that the human leukocyte antigen (HLA) system may play a part in development of the illness, but the causal HLA variant(s) remain(s) unclear. Previous studies showed that the DRB1*0101 and DRB1*13 alleles might be associated with a high risk of schizophrenia. Therefore, the...
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