Study of the possible association of HLA class II, CD4, and CD3 polymorphisms with schizophrenia.

doi:10.1002/ajmg.1320540417

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Article

Study of the possible association of HLA class II, CD4, and CD3 polymorphisms with schizophrenia.

American journal of medical genetics - 15 Dec 1994

Zamani M G, De Hert M, Spaepen M, Hermans M, Marynen P, Cassiman J J, Peuskens J

Abstract excerpt

In the present study the HLA-DRB and DPB1 alleles as well as CD4 and CD3 polymorphisms were tested in 100 Belgian schizophrenic patients and 204 controls. Our results indicate a significant negative association of the DPB1 0101 allele with schizophrenia (relative risk [RR] = 0.27). Furthermore a...

Topics

Adolescent
Adult
Age of Onset
Aged
Alleles
Antigens, CD
Base Sequence
CD3 Complex
CD4 Antigens
Child
DNA Primers
Female
HLA-D Antigens
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Male
Middle Aged

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