Article
Genome-wide search for markers associated with bovine spongiform encephalopathy.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2002
Hernández-Sánchez Jules, Waddington Dave, Wiener Pamela, Haley Chris S, Williams John L
Abstract excerpt
A genome-wide search for markers associated with BSE incidence was performed by using Transmission-Disequilibrium Tests (TDTs). Significant segregation distortion, i.e., unequal transmission probabilities of alleles within a locus, was found for three marker loci on Chromosomes (Chrs) 5, 10, and 20. Although TDTs are robust to false associations owing to hidden population substructures, it cannot distinguish...
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