Article
Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease.
The New England journal of medicine - 28 Mar 2002
Herrington David M, Howard Timothy D, Hawkins Gregory A, Reboussin David M, Xu Jianfeng, Zheng Siqun L, Brosnihan K Bridget, Meyers Deborah A, Bleecker Eugene R
Abstract excerpt
BACKGROUND: Sequence variants in the gene encoding estrogen receptor alpha (ER-alpha) may modify the effects of hormone-replacement therapy on levels of high-density lipoprotein (HDL) cholesterol and other outcomes related to estrogen treatment in postmenopausal women. METHODS: We characterized 309 women with coronary artery disease who were enrolled in the Estrogen Replacement and Atherosclerosis trial with...
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