Article
Inflammatory response of coronary artery disease postmenopausal women is associated with the IVS1-397T > C estrogen receptor alpha polymorphism.
Clinical immunology (Orlando, Fla.) - 1 Mar 2009
Myśliwska Jolanta, Rutkowska Aleksandra, Hak Lukasz, Siebert Janusz, Szyndler Krzysztof, Rachoń Dominik
Abstract excerpt
We analyzed the relationship between the IVS1-397T > C polymorphism of estrogen receptor alpha gene and inflammatory response of eighty postmenopausal women with an established coronary artery disease (CAD). We found that the IVS1-397T allele carriers exhibited an enhanced inflammatory response in vivo and in vitro. These patients had a higher number of total monocytes and their CD14(+)CD16(+) inflammatory subset...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.