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Article

Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomes.

The Journal of biological chemistry - 14 Jun 2002

Conway Colin, McCulloch Richard, Ginger Michael L, Robinson Nicholas P, Browitt Alison, Barry J David

Abstract excerpt

Trypanosome antigenic variation, involving differential expression of variant surface glycoprotein (VSG) genes, has a strong association with telomeres and with DNA recombination. All expressed VSGs are telomeric, and differential activation involves recombination into the telomeric environment or silencing/activation of subtelomeric promoters. A number of pathogen contingency gene systems associated with immune...

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PMID: 11919193
DOI: 10.1074/jbc.M200550200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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