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Article

SmpB functions in various steps of trans-translation.

Nucleic acids research - 1 Apr 2002

Hanawa-Suetsugu Kyoko, Takagi Mitsuru, Inokuchi Hachiro, Himeno Hyouta, Muto Akira

Abstract excerpt

tmRNA has a dual function as a tRNA and an mRNA to facilitate trans-translation, in which a ribosome can switch between translation of a truncated mRNA and the tmRNA's tag sequence. SmpB is a tmRNA binding protein that has been identified to be essential for trans-translation in vivo. To further study the function of SmpB, an S30 fraction from an Escherichia coli strain, in which the set of genes for SmpB and...

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Identifiers

PMID: 11917023
DOI: 10.1093/nar/30.7.1620
PMCID: PMC101834

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Source receipt: pubmed, retrieved 7 Sept 2026.

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SmpB functions in various steps of trans-translation.PMID 11917023Read ↗

A functional interaction of SmpB with tmRNA for determination of the resuming point of trans-translation.Semantic proximity Read ↗

A previously uncharacterized role for small protein B (SmpB) in transfer messenger RNA-mediated trans-translation.Semantic proximity Read ↗

SmpB contributes to reading frame selection in the translation of transfer-messenger RNA.Semantic proximity Read ↗

Pre-binding of small protein B to a stalled ribosome triggers trans-translation.Semantic proximity Read ↗

SmpB, a unique RNA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA).Semantic proximity Read ↗

Detection of tmRNA-mediated trans-translation products in Bacillus subtilis.Semantic proximity Read ↗

RNase R degrades non-stop mRNAs selectively in an SmpB-tmRNA-dependent manner.Semantic proximity Read ↗

Determinants on tmRNA for initiating efficient and precise trans-translation: some mutations upstream of the tag-encoding sequence of Escherichia coli tmRNA shift the initiation point of trans-translation in vitro.Semantic proximity Read ↗

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Interaction of 10Sa RNA with ribosomes in Escherichia coli.Semantic proximity Read ↗

In vitro trans-translation of Thermus thermophilus: ribosomal protein S1 is not required for the early stage of trans-translation.Semantic proximity Read ↗

tmRNA determinants required for facilitating nonstop mRNA decay.Semantic proximity Read ↗

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