Article
Detection of tmRNA-mediated trans-translation products in Bacillus subtilis.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Mar 2002
Fujihara Ai, Tomatsu Hisashi, Inagaki Sachi, Tadaki Toshimasa, Ushida Chisato, Himeno Hyouta, Muto Akira
Abstract excerpt
BACKGROUND: Bacterial tmRNA (10Sa RNA) is involved in a trans-translation reaction, which contributes to the degradation of incompletely synthesized peptides and the recycling of stalled ribosomes. To investigate the physiological roles of this reaction in Bacillus subtilis, we devised a system for detecting the proteins that are subject to in vivo trans-translation. RESULTS: The wild-type tmRNA gene (ssrA) in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
