Article
Relation between disease phenotype and HLA-DQ genotype in diabetic patients diagnosed in early adulthood.
The Journal of clinical endocrinology and metabolism - 1 Jun 2002
Weets Ilse, Siraux Valerie, Daubresse Jean-Claude, De Leeuw Ivo H, Féry Francoise, Keymeulen Bart, Krzentowski Georges, Letiexhe Michel, Mathieu Chantal, Nobels Frank, Rottiers Raoul, Scheen André, Van Gaal Luc, Schuit Frans C, Van der Auwera Bart, Rui Mao, De Pauw Pieter, Kaufman Leonard, Gorus Frans K
Abstract excerpt
We investigated inaugural disease phenotype in relation to the presence or absence of diabetes-associated autoantibodies and human leukocyte antigen (HLA) DQ risk genotypes in adult-onset diabetic patients. Blood samples and questionnaires were obtained from 1584 recent-onset Belgian Caucasian patients (age 15-39 yr at diagnosis of primary diabetes) who were recruited by the Belgian Diabetes Registry over an...
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