Article
Massive repopulation of rat liver by transplantation of hepatocytes into specific lobes of the liver and ligation of portal vein branches to other lobes.
Transplantation - 15 Jul 1997
Ilan Y, Roy-Chowdhury N, Prakash R, Jona V, Attavar P, Guha C, Tada K, Roy-Chowdhury J
Abstract excerpt
An important consideration in application of hepatocyte transplantation is whether the number of engrafted hepatocytes is sufficient to achieve the desired effect. Here we have evaluated the proliferative potential of transplanted primary hepatocytes during regeneration of hepatic lobes. Two million hepatocytes isolated from congeneic normal Wistar-RHA rats were injected into the main portal vein of deficient,...
Topics
- Animals
- Apoptosis
- Atrophy
- Bile Pigments
- Bilirubin
- Cell Division
- Cell Transplantation
- Genotype
- Glucuronosyltransferase
- Immunoblotting
- Ligation
- Liver
- Liver Regeneration
- Portal Vein