Article
Target gene mutation profile differs between gastrointestinal and endometrial tumors with mismatch repair deficiency.
Cancer research - 15 Mar 2002
Duval Alex, Reperant Maryline, Compoint Aurore, Seruca Raquel, Ranzani Guglielmina N, Iacopetta Barry, Hamelin Richard
Abstract excerpt
Mutation frequencies at 25 genes containing coding repeats were compared in colorectal, gastric, and endometrial mismatch repair-deficient (MSI-H) tumors. The overall number of mutations was significantly lower in endometrial than in gastrointestinal MSI-H cancers. Using a likelihood statistical...
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