Article
Plasminogen activator inhibitor-I (PAI-I) polymorphisms in patients with obstructive sleep apnoea.
Respiratory medicine - 1 Mar 2002
Barceló A, Llompart E, Barbé F, Morlá M, Vila M, Agustí A G N
Abstract excerpt
Cardiovascular diseases are frequent among patients with the obstructive sleep apnoea syndrome (OSAS), The aetiopathogenesis of this association is unclear. Type 1 plasminogen activator inhibitor (PAI-1) is one of the primary regulators of the fibrinolytic system. A reported association between PAI-1 activity and an insertion/deletion polymorphism (4G/5G) in the promoter region of the PAI-1 gene suggests a...
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