Article
Relationship of plasminogen activator inhibitor 1 gene 4G/5G polymorphisms to hypertension in Korean women.
Chinese medical journal - 1 Apr 2012
Kim Kyu-nam, Kim Kwang-min, Kim Bom-taeck, Joo Nam-seok, Cho Doo-yeoun, Lee Duck-joo
Abstract excerpt
BACKGROUND: Hypertension (HTN) is a major determinant of various cardiovascular events. Plasma levels of plasminogen activator inhibitor 1 (PAI-1) modulate this risk. A deletion/insertion polymorphism within the PAI-1 loci (4G/4G, 4G/5G, 5G/5G) affects the expression of this gene. The present study investigated the association between PAI-1 loci polymorphisms and HTN in Korean women. METHODS: Korean women (n =...
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