Article
Evaluation of Fibrinolytic Inhibitors: Alpha-2-Antiplasmin and Plasminogen Activator Inhibitor 1 in Patients with Obstructive Sleep Apnoea.
PloS one - 1 Jan 2016
Zakrzewski Maciej, Zakrzewska Ewelina, Kiciński Paweł, Przybylska-Kuć Sylwia, Dybała Andrzej, Myśliński Wojciech, Pastryk Jolanta, Tomaszewski Tomasz, Mosiewicz Jerzy
Abstract excerpt
Obstructive sleep apnoea (OSA) induces thrombophilia and reduces fibrinolysis. Alpha-2-antiplasmin (a-2-AP) and plasminogen activator inhibitor 1 (PAI-1) are major inhibitors of the fibrinolytic system. Increased concentrations of these factors are associated with a higher risk of cardiovascular diseases. The aim of this study was to assess plasma a-2-AP and PAI-1 in patients with OSA and evaluate correlations...
Topics
- Adult
- Biomarkers
- Blood Chemical Analysis
- Blood Coagulation
- Blood Gas Analysis
- Case-Control Studies
- Comorbidity
- Female
- Humans
- Male
- Middle Aged
- Phenotype
- Plasminogen Activator Inhibitor 1