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Article

Complementation of a p300/CBP defective-binding mutant of adenovirus E1a by human papillomavirus E6 proteins.

The Journal of general virology - 1 Apr 2002

Bernat Agnieszka, Massimi Paola, Banks Lawrence

Abstract excerpt

Previous studies have shown that the human papillomavirus type 16 (HPV-16) E6 protein binds to p300/CBP and abrogates its transcriptional co-activator function. However, there is little information on the biological consequences of this interaction and discrepancy as to whether the interaction is high-risk E6 specific or not. We performed a series of studies to compare the interactions of HPV-18 and HPV-11 E6...

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Source

Identifiers

PMID: 11907332
DOI: 10.1099/0022-1317-83-4-829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Complementation of a p300/CBP defective-binding mutant of adenovirus E1a by human papillomavirus E6 proteins.PMID 11907332Read ↗

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.Semantic proximity Read ↗

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Cutaneous Papillomavirus E6 Proteins Must Interact with p300 and Block p53-Mediated Apoptosis for Cellular Immortalization and TumorigenesisSemantic proximity Read ↗

Interaction between the HPV E7 oncoprotein and the transcriptional coactivator p300.Semantic proximity Read ↗

Identification of specific amino acid residues of adenovirus 12 E1A involved in transformation and p300 binding.Semantic proximity Read ↗

The ability of E1A to rescue ras-induced premature senescence and confer transformation relies on inactivation of both p300/CBP and Rb family proteins.Semantic proximity Read ↗

The transcriptional co-activator proteins p300 and CBP stimulate adenovirus E1A conserved region 1 transactivation independent of a direct interaction.Semantic proximity Read ↗

Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP.Semantic proximity Read ↗

Direct Interaction between Nucleosome Assembly Protein 1 and the Papillomavirus E2 Proteins Involved in Activation of TranscriptionSemantic proximity Read ↗

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