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Beta-HPV 5 and 8 E6 Promote p300 Degradation by Blocking AKT/p300 Association

25 Aug 2011

Abstract excerpt

The E6 oncoprotein from high-risk genus alpha human papillomaviruses (α-HPVs), such as HPV 16, has been well characterized with respect to the host-cell proteins it interacts with and corresponding signaling pathways that are disrupted due to these interactions. Less is known regarding the interacting partners of E6 from the genus beta papillomaviruses (β-HPVs); however, it is generally thought that β-HPV E6...

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PMID: 21901101
DOI: 10.1371/journal.ppat.1002211

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