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Article

Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic livers

1 Feb 2002

Abstract excerpt

BACKGROUND/AIMS: The catalytic subunit of human telomerase (hTERT) is known to be expressed in a variety of malignant tumours, including hepatocellular carcinoma (HCC). We studied hTERT expression in regenerative and precancerous lesions arising in cirrhosis. METHODS/RESULTS: As shown by in situ hybridisation, hTERT mRNA was absent in normal liver, but present in varying numbers of hepatocytes and HCC cells of...

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PMID: 11906620
DOI: 10.1046/j.0106-9543.2001.01594.x

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