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Article

High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma

27 Jul 2004

Abstract excerpt

Telomerase, an enzyme related with cellular immortality, has been extensively studied in many kinds of malignant tumours for clinical diagnostic or prognostic utilities. Telomerase activity is mainly regulated by the expression of hTERT (human telomerase reverse transcriptase), which is a catalytic component of human telomerase. To evaluate whether the levels of hTERT mRNA provides a molecular marker of...

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PMID: 15280920
DOI: 10.1038/sj.bjc.6602054

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