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Article

Differential diagnosis of small hepatocellular nodules in cirrhosis: surrogate histological criteria of TERT promoter mutations.

Histopathology - 1 Feb 2024

Beaufrère Aurélie, Paisley Sarah, Ba Ibrahima, Laouirem Samira, Priori Victoria, Cazier Hélène, Favre Loëtitia, Cauchy François, Lesurtel Mickael, Calderaro Julien, Kannengiesser Caroline, Paradis Valérie

Abstract excerpt

AIMS: The differential diagnosis of small hepatocellular nodules in cirrhosis between dysplastic nodules and hepatocellular carcinoma (HCC) remains challenging on biopsy. As TERT promoter (pTERT) mutations may indicate the nodules already engaged in the malignant process, the aim of this study was to identify histological criteria associated with pTERT mutations by detecting these mutations by ddPCR in small...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37903649
DOI: 10.1111/his.15086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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