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Article

Cysteine-free mutant of aequorin as a photolabel in immunoassay development.

Bioconjugate chemistry - 1 Jan 2000

Shrestha Suresh, Paeng Insook R, Deo Sapna K, Daunert Sylvia

Abstract excerpt

The bioluminescent protein aequorin is a sensitive label that has been employed in a number of analytical applications. A mutant of aequorin with enhanced stability produced recombinantly in our laboratory has been employed as a label in the development of an immunoassay for digoxin. Digoxin is a cardiac glycoside used in the treatment of congestive heart failure. This drug has a very narrow therapeutic range of...

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Identifiers

PMID: 11906264
DOI: 10.1021/bc010044c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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